7JX9
The crystal structure of human ornithine aminotransferase with an intermediate bound during inactivation by (1S,3S)-3-amino-4-(hexafluoropropan-2-ylidenyl)-cyclopentane-1-carboxylic acid.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Ornithine aminotransferase, mitochondrial | polymer | 404 | 44860.3 | 3 | UniProt (P04181) Pfam (PF00202) | Homo sapiens (Human) | Ornithine delta-aminotransferase,Ornithine--oxo-acid aminotransferase |
| 2 | D, F, G (A, B, C) | (1S,3S,4S)-3-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-(1,1,3,3,3-pentafluoroprop-1-en-2-yl)cyclopentane-1-carboxylic acid | non-polymer | 488.3 | 3 | Chemie (IF1) | |||
| 3 | E, H (A, C) | N-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]glycine | non-polymer | 179.2 | 2 | Chemie (VLS) | |||
| 4 | I, J, K (A, B, C) | water | water | 18.0 | 615 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 134581.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1823.2 | |
| All* | Total formula weight | 136404.2 |
