7JWS
Crystal structure of human ALDH1A1 bound to compound (R)-28
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Retinal dehydrogenase 1 | polymer | 501 | 54897.6 | 1 | UniProt (V9HW83) Pfam (PF00171) UniProt (by SIFTS) (P00352) In PDB | Homo sapiens (Human) | RalDH1, ALDH-E1, ALHDII, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic |
2 | A | YTTERBIUM (III) ION | non-polymer | 173.0 | 2 | Chemie (YB) | |||
3 | A | 1-methyl-5-phenyl-6-{[(1R)-1-phenylethyl]sulfanyl}-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | non-polymer | 362.4 | 1 | Chemie (VLY) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence modifications
A: 1 - 501 (UniProt: V9HW83)
PDB | External Database | Details |
---|---|---|
Ser 121 | Asn 121 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 54897.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 744.0 | |
All* | Total formula weight | 55641.6 |