7JPS

ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Origin recognition complex subunit 1	polymer	392	44310.9	1	UniProt (Q13415) Pfam (PF00004) Pfam (PF17872) Pfam (PF09079)	Homo sapiens (Human)	Replication control protein 1
2	B (B)	Origin recognition complex subunit 2	polymer	577	66063.4	1	UniProt (Q13416) Pfam (PF04084) Pfam (PF24882)	Homo sapiens (Human)
3	C (C)	Origin recognition complex subunit 3	polymer	712	82436.1	1	UniProt (Q9UBD5) Pfam (PF07034) Pfam (PF19675) Pfam (PF18137)	Homo sapiens (Human)	Origin recognition complex subunit Latheo
4	D (D)	Origin recognition complex subunit 4	polymer	436	50443.3	1	UniProt (O43929) Pfam (PF14629) Pfam (PF13191)	Homo sapiens (Human)
5	E (E)	Origin recognition complex subunit 5	polymer	435	50349.9	1	UniProt (O43913) Pfam (PF13191) Pfam (PF21639) Pfam (PF14630)	Homo sapiens (Human)
6	F (F)	DNA (5'-D(*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*AP*T)-3')	polymer	13	3972.6	1		Spodoptera frugiperda
7	G (G)	DNA (5'-D(*AP*TP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*T)-3')	polymer	13	3963.6	1		Spodoptera frugiperda
8	H, K, M (A, D, E)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	3	Chemie (ATP)
9	I, L, N (A, D, E)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
10	J (B)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)

Sequence modifications

A: 471 - 861 (UniProt: Q13415)

PDB	External Database	Details
Met 470	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	301539.9
Non-Polymers*	Number of molecules	7
	Total formula weight	1633.6
All*	Total formula weight	303173.4

*Water molecules are not included.