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7JPR

ORC-OPEN: Human Origin Recognition Complex (ORC) in an open conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AOrigin recognition complex subunit 1polymer39244310.91UniProt (Q13415)
Pfam (PF00004)
Pfam (PF17872)
Pfam (PF09079)
In PDB
Homo sapiens (Human)Replication control protein 1
2BOrigin recognition complex subunit 2polymer57766063.41UniProt (Q13416)
Pfam (PF04084)
In PDB
Homo sapiens (Human)
3COrigin recognition complex subunit 3polymer71282436.11UniProt (Q9UBD5)
Pfam (PF07034)
Pfam (PF19675)
Pfam (PF18137)
In PDB
Homo sapiens (Human)Origin recognition complex subunit Latheo
4DOrigin recognition complex subunit 4polymer43650443.31UniProt (O43929)
Pfam (PF13191)
Pfam (PF14629)
In PDB
Homo sapiens (Human)
5EOrigin recognition complex subunit 5polymer43550349.91UniProt (O43913)
Pfam (PF13191)
Pfam (PF21639)
Pfam (PF14630)
In PDB
Homo sapiens (Human)
6A, D, EADENOSINE-5'-TRIPHOSPHATEnon-polymer507.23Chemie (ATP)
7A, D, EMAGNESIUM IONnon-polymer24.33Chemie (MG)
Sequence modifications
A: 471 - 861 (UniProt: Q13415)
PDBExternal DatabaseDetails
Met 470-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight293603.6
Non-Polymers*Number of molecules6
Total formula weight1594.5
All*Total formula weight295198.1
*Water molecules are not included.

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PDB entries from 2024-07-24

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