7JPI
Crystal structure of EBOV glycoprotein with modified HR2 stalk at 2.3A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Envelope glycoprotein | polymer | 297 | 33246.6 | 1 | Pfam (PF01611) UniProt (by SIFTS) (Q05320) In PDB | Ebola virus - Mayinga Zaire 1976 (ZEBOV) | |
| 2 | B | Envelope glycoprotein | polymer | 165 | 18499.0 | 1 | UniProt (Q05320) In PDB | Ebola virus - Mayinga Zaire 1976 (ZEBOV) | GP1,2,GP |
| 3 | F, H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | C | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G09724ZC) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 8 | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
B: 502 - 637 (UniProt: Q05320)
| PDB | External Database | Details |
|---|---|---|
| Leu 615 | Trp 615 | engineered mutation |
| Ala 638 | - | expression tag |
| Ser 639 | - | expression tag |
| Gly 640 | - | expression tag |
| Tyr 641 | - | expression tag |
| Ile 642 | - | expression tag |
| Pro 643 | - | expression tag |
| Glu 644 | - | expression tag |
| Ala 645 | - | expression tag |
| Pro 646 | - | expression tag |
| Arg 647 | - | expression tag |
| Asp 648 | - | expression tag |
| Gly 649 | - | expression tag |
| Gln 650 | - | expression tag |
| Ala 651 | - | expression tag |
| Tyr 652 | - | expression tag |
| Val 653 | - | expression tag |
| Arg 654 | - | expression tag |
| Lys 655 | - | expression tag |
| Asp 656 | - | expression tag |
| Gly 657 | - | expression tag |
| Glu 658 | - | expression tag |
| Trp 659 | - | expression tag |
| Val 660 | - | expression tag |
| Leu 661 | - | expression tag |
| Leu 662 | - | expression tag |
| Ser 663 | - | expression tag |
| Thr 664 | - | expression tag |
| Phe 665 | - | expression tag |
| Leu 666 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51745.5 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1921.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 500.4 | |
| All* | Total formula weight | 54167.7 |
