7JN2
The crystal structure of Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder441 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Papain-like protease | polymer | 318 | 35943.8 | 1 | UniProt (P0DTC1) Pfam (PF08715) UniProt (by SIFTS) (P0DTD1) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Non-structural protein 3,nsp3, PL2-PRO, Papain-like proteinase, PL-PRO |
| 2 | B (A) | 3-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide | non-polymer | 304.4 | 1 | Chemie (Y41) | |||
| 3 | C, D, E, F, G (A) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 4 | H, I, J, K (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | L (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | M, N, O, P, Q (A) | UNKNOWN ATOM OR ION | non-polymer | 5 | Chemie (UNX) | ||||
| 7 | R (A) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A: 1 - 315 (UniProt: P0DTC1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35943.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 832.3 | |
| All* | Total formula weight | 36776.0 |
