7JM5
Crystal structure of KDM4B in complex with QC6352
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lysine-specific demethylase 4B | polymer | 367 | 42209.9 | 2 | UniProt (O94953) Pfam (PF02375) Pfam (PF02373) | Homo sapiens (Human) | JmjC domain-containing histone demethylation protein 3B,Jumonji domain-containing protein 2B,[histone H3]-trimethyl-L-lysine(9) demethylase 4B |
| 2 | C, E (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 3 | D, G (A, B) | 3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid | non-polymer | 387.5 | 2 | Chemie (9DJ) | |||
| 4 | F (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 366 (UniProt: O94953)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84419.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 957.7 | |
| All* | Total formula weight | 85377.6 |
