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7JKY

Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-126

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ABromodomain-containing protein 4polymer12715123.41UniProt (O60885)
Pfam (PF00439)
In PDB
Homo sapiens (Human)Protein HUNK1
2AN-(1-[1,1-di(pyridin-2-yl)ethyl]-6-{1-methyl-6-oxo-5-[(piperidin-4-yl)amino]-1,6-dihydropyridin-3-yl}-1H-indol-4-yl)ethanesulfonamidenon-polymer611.81Chemie (YF6)
3ASODIUM IONnon-polymer23.01Chemie (NA)
4waterwater18.0170Chemie (HOH)
Sequence modifications
A: 44 - 168 (UniProt: O60885)
PDBExternal DatabaseDetails
Leu 42-expression tag
Glu 43-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight15123.4
Non-Polymers*Number of molecules2
Total formula weight634.7
All*Total formula weight15758.1
*Water molecules are not included.

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PDB entries from 2024-06-26

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