7JK6

Structure of Drosophila ORC in the active conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (D)	Origin recognition complex subunit 4	polymer	462	52277.1	1	UniProt (Q9W102) Pfam (PF13191) Pfam (PF14629)	Drosophila melanogaster (Fruit fly)
2	B (E)	Origin recognition complex subunit 5	polymer	460	52175.1	1	UniProt (Q24169) Pfam (PF13191) Pfam (PF21639) Pfam (PF14630)	Drosophila melanogaster (Fruit fly)	Orc5
3	C (A)	Origin recognition complex subunit 1	polymer	488	54485.6	1	UniProt (O16810) Pfam (PF00004) Pfam (PF17872) Pfam (PF09079)	Drosophila melanogaster (Fruit fly)	DmORC1
4	D (B)	Origin recognition complex subunit 2	polymer	618	69086.4	1	UniProt (Q24168) Pfam (PF04084)	Drosophila melanogaster (Fruit fly)	DmORC2
5	E (C)	Origin recognition complex subunit 3	polymer	721	82364.5	1	UniProt (Q7K2L1) Pfam (PF07034) Pfam (PF19675) Pfam (PF18137)	Drosophila melanogaster (Fruit fly)	FI24229p1,GH28787p,LP02234p1,Orc3,isoform A,isoform B
6	F (F)	Origin recognition complex subunit 6	polymer	257	29284.1	1	UniProt (Q9Y1B2) Pfam (PF05460) Pfam (PF21913)	Drosophila melanogaster (Fruit fly)	Orc6
7	G, I, K (D, E, A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	3	Chemie (ATP)
8	H, J, L (D, E, A)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)

Sequence modifications

D: 1 - 459 (UniProt: Q9W102)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

A: 440 - 924 (UniProt: O16810)

PDB	External Database	Details
Ser 437	-	expression tag
Asn 438	-	expression tag
Ala 439	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	339672.9
Non-Polymers*	Number of molecules	6
	Total formula weight	1594.5
All*	Total formula weight	341267.4

*Water molecules are not included.