7JK3
Structure of Drosophila ORC bound to GC-rich DNA and Cdc6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Origin recognition complex subunit 2 | polymer | 618 | 69086.4 | 1 | UniProt (Q24168) Pfam (PF04084) | Drosophila melanogaster (Fruit fly) | DmORC2 |
| 2 | B (C) | Origin recognition complex subunit 3 | polymer | 721 | 82364.5 | 1 | UniProt (Q7K2L1) Pfam (PF07034) Pfam (PF19675) Pfam (PF18137) | Drosophila melanogaster (Fruit fly) | FI24229p1,GH28787p,LP02234p1,Orc3,isoform A,isoform B |
| 3 | C (D) | Origin recognition complex subunit 4 | polymer | 462 | 52277.1 | 1 | UniProt (Q9W102) Pfam (PF13191) Pfam (PF14629) | Drosophila melanogaster (Fruit fly) | Orc4 |
| 4 | D (E) | Origin recognition complex subunit 5 | polymer | 460 | 52175.1 | 1 | UniProt (Q24169) Pfam (PF13191) Pfam (PF21639) Pfam (PF14630) | Drosophila melanogaster (Fruit fly) | Orc5 |
| 5 | E (F) | Origin recognition complex subunit 6 | polymer | 257 | 29284.1 | 1 | UniProt (Q9Y1B2) Pfam (PF05460) Pfam (PF21913) | Drosophila melanogaster (Fruit fly) | Orc6 |
| 6 | F (A) | Origin recognition complex subunit 1 | polymer | 488 | 54485.6 | 1 | UniProt (O16810) Pfam (PF00004) Pfam (PF17872) Pfam (PF09079) | Drosophila melanogaster (Fruit fly) | DmORC1 |
| 7 | G (G) | Cell division control protein | polymer | 424 | 48049.5 | 1 | UniProt (Q9VSM9) Pfam (PF13401) Pfam (PF22606) Pfam (PF09079) | Drosophila melanogaster (Fruit fly) | Cdc6 |
| 8 | H (H) | DNA (33-MER) | polymer | 60 | 18679.9 | 1 | synthetic construct | ||
| 9 | I (I) | DNA (33-MER) | polymer | 60 | 18315.7 | 1 | synthetic construct | ||
| 10 | J, L, N, P (D, E, A, G) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 11 | K, M, O, Q (D, E, A, G) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) |
Sequence modifications
D: 1 - 459 (UniProt: Q9W102)
A: 440 - 924 (UniProt: O16810)
G: 242 - 662 (UniProt: Q9VSM9)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 437 | - | expression tag |
| Asn 438 | - | expression tag |
| Ala 439 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 239 | - | expression tag |
| Asn 240 | - | expression tag |
| Ala 241 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 424717.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2125.9 | |
| All* | Total formula weight | 426843.9 |
