7JJC

Crystal structure of neuropilin-1 b1 domain in complex with SARS-CoV-2 S1 C-end rule (CendR) peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Neuropilin-1	polymer	166	18766.2	4	UniProt (O14786) Pfam (PF00754) In PDB	Homo sapiens (Human)	Vascular endothelial cell growth factor 165 receptor
2	E, F, G, H	Spike protein S1	polymer	7	859.0	4	UniProt (P0DTC2) In PDB	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein,Spike glycoprotein
3	A, B, C, D	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
4	C, D	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5		water	water		18.0	128	Chemie (HOH)

Sequence modifications

A, B, C, D: 273 - 427 (UniProt: O14786)

PDB	External Database	Details
Gly -10	-	expression tag
Ser -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	78500.5
Non-Polymers*	Number of molecules	7
	Total formula weight	700.8
All*	Total formula weight	79201.3

*Water molecules are not included.