7JJC
Crystal structure of neuropilin-1 b1 domain in complex with SARS-CoV-2 S1 C-end rule (CendR) peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Neuropilin-1 | polymer | 166 | 18766.2 | 4 | UniProt (O14786) Pfam (PF00754) | Homo sapiens (Human) | Vascular endothelial cell growth factor 165 receptor |
| 2 | E, F, G, H (E, F, G, H) | Spike protein S1 | polymer | 7 | 859.0 | 4 | UniProt (P0DTC2) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein,Spike glycoprotein |
| 3 | I, J, K, N (A, B, C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 4 | L, M, O (C, D) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | P, Q, R, S, T... (A, B, C, D, F...) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 273 - 427 (UniProt: O14786)
| PDB | External Database | Details |
|---|---|---|
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Asn -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 78500.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 700.8 | |
| All* | Total formula weight | 79201.3 |
