7JHI
Structure of human beta 1,3-N-acetylglucosaminyltransferase 2 iodide-derivative
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 | polymer | 384 | 44769.9 | 4 | UniProt (Q9NY97) Pfam (PF01762) | Homo sapiens (Human) | Beta-1,3-N-acetylglucosaminyltransferase 1,Beta3Gn-T1,3-galactosyltransferase 7,b3Gal-T7,Beta-3-Gx-T7,UDP-Gal:beta-GlcNAc beta-1,UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2,Beta3Gn-T2,UDP-galactose:beta-N-acetylglucosamine beta-1 |
| 2 | E, H (E, H) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 3 | F (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G (G) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 5 | I, LA (A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | J, MA, Y (A, C, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 7 | K, NA (A, C) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 8 | AA, AB, BA, BB, CA... (B, D, A, C) | IODIDE ION | non-polymer | 126.9 | 41 | Chemie (IOD) | |||
| 9 | IB, JB, W, X, YA (D, A, C) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 10 | ZA (C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 11 | KB, LB, MB, NB (A, B, C, D) | water | water | 18.0 | 424 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 30 - 397 (UniProt: Q9NY97)
| PDB | External Database | Details |
|---|---|---|
| Met 14 | - | initiating methionine |
| His 15 | - | expression tag |
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| His 19 | - | expression tag |
| His 20 | - | expression tag |
| His 21 | - | expression tag |
| His 22 | - | expression tag |
| Glu 23 | - | expression tag |
| Asn 24 | - | expression tag |
| Leu 25 | - | expression tag |
| Tyr 26 | - | expression tag |
| Phe 27 | - | expression tag |
| Gln 28 | - | expression tag |
| Gly 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 179079.6 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2346.2 | |
| Non-Polymers* | Number of molecules | 54 |
| Total formula weight | 6898.2 | |
| All* | Total formula weight | 188324.0 |
