7JGW
Crystal structure of BCL-XL in complex with COMPOUND 1620116, CRYSTAL FORM 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bcl-2-like protein 1 | polymer | 158 | 17918.0 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) | Homo sapiens (Human) | Bcl2-L-1,Apoptosis regulator Bcl-X,Bcl2-L-1,Apoptosis regulator Bcl-X |
| 2 | B (A) | 6-[(8E)-8-{2-[4-(benzylcarbamoyl)-1,3-thiazol-2-yl]hydrazinylidene}-5,6,7,8-tetrahydronaphthalen-2-yl]-3-(2-phenylethoxy)pyridine-2-carboxylic acid | non-polymer | 617.7 | 1 | Chemie (V9S) | |||
| 3 | C (A) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A: 1 - 26 (UniProt: Q07817)
A: 83 - 209 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17918.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 617.7 | |
| All* | Total formula weight | 18535.7 |
