7JG4
Human GAR transformylase in complex with GAR substrate and AGF131 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Trifunctional purine biosynthetic protein adenosine-3 | polymer | 210 | 22810.1 | 1 | UniProt (P22102) Pfam (PF00551) In PDB | Homo sapiens (Human) | |
| 2 | A | GLYCINAMIDE RIBONUCLEOTIDE | non-polymer | 284.2 | 1 | Chemie (GAR) | |||
| 3 | A | N-(5-{3-[(1S,7R,8R,9S)-4-amino-2-oxo-7lambda~4~-thia-3,5-diazatetracyclo[4.3.0.0~1,7~.0~7,9~]nona-3,5-dien-8-yl]propyl}thiophene-2-carbonyl)-L-glutamic acid | non-polymer | 464.5 | 1 | Chemie (V9V) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A: 808 - 1010 (UniProt: P22102)
| PDB | External Database | Details |
|---|---|---|
| Met 807 | - | initiating methionine |
| His 1011 | - | expression tag |
| His 1012 | - | expression tag |
| His 1013 | - | expression tag |
| His 1014 | - | expression tag |
| His 1015 | - | expression tag |
| His 1016 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22810.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 771.7 | |
| All* | Total formula weight | 23581.8 |
