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7JG3

Human GAR transformylase in complex with GAR substrate and AGF103 inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Trifunctional purine biosynthetic protein adenosine-3polymer21022810.11UniProt (P22102)
Pfam (PF00551)
Homo sapiens (Human)
2B
(A)
GLYCINAMIDE RIBONUCLEOTIDEnon-polymer284.21Chemie (GAR)
3C
(A)
N-{5-[4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl]furan-2-carbonyl}-L-glutamic acidnon-polymer462.51Chemie (V9A)
4D
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
5E
(A)
waterwater18.0114Chemie (HOH)
Sequence modifications
A: 808 - 1010 (UniProt: P22102)
PDBExternal DatabaseDetails
Met 807-initiating methionine
His 1011-expression tag
His 1012-expression tag
His 1013-expression tag
His 1014-expression tag
His 1015-expression tag
His 1016-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight22810.1
Non-Polymers*Number of molecules3
Total formula weight769.6
All*Total formula weight23579.8
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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