7IK7
Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the O'Brien group -- Crystal Structure of SARS-CoV-2 NSP3 Macrodomain in complex with POB0218 (Mac1-x10586)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Papain-like protease nsp3 | polymer | 170 | 18275.8 | 1 | UniProt (P0DTD1) Pfam (PF01661) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 3,nsp3,PL2-PRO,Papain-like proteinase,PL-PRO |
| 2 | B (A) | (2P)-2-[2-(ethylamino)-1,3-benzothiazol-6-yl]cyclopent-1-ene-1-carboxylic acid | non-polymer | 288.4 | 1 | Chemie (A1CMD) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D (A) | water | water | 18.0 | 191 | Chemie (HOH) |
Sequence modifications
A: 2 - 170 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18275.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 366.5 | |
| All* | Total formula weight | 18642.3 |
