7IAT
Crystal structure of Zika NS2B-NS3 protease in complex with fragment EOS102811 from ECBL-96
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | NS2B co-factor | polymer | 53 | 5865.4 | 2 | UniProt (A0A142IX72) | Zika virus | |
| 2 | B, D (B, D) | NS3 protease | polymer | 176 | 18877.4 | 2 | UniProt (A0A142IX72) | Zika virus | |
| 3 | E (D) | 2,3-dihydro-1H-1lambda~6~,2-benzothiazole-1,1-dione | non-polymer | 169.2 | 1 | Chemie (A1CDM) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A, C: 45 - 96 (UniProt: A0A142IX72)
B, D: 2 - 177 (UniProt: A0A142IX72)
| PDB | External Database | Details |
|---|---|---|
| Met 44 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Ser 143 | Cys 1639 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 49485.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 169.2 | |
| All* | Total formula weight | 49654.8 |
