7I9E

Crystal Structure of 18 bound to the PH domain of Btk

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Tyrosine-protein kinase BTK	polymer	169	19983.0	4	UniProt (Q06187) Pfam (PF00169) Pfam (PF00779)	Homo sapiens (human)	Agammaglobulinemia tyrosine kinase,ATK,B-cell progenitor kinase,BPK,Bruton tyrosine kinase
2	E, G, J (A, B, C)	(6S)-6-(2,6-dimethoxyphenyl)-4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid	non-polymer		302.3	3	Chemie (A1B6N)	Homo sapiens
3	F, H, K, M (A, B, C, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN) PubChem (32051)
4	I, L, N (B, C, D)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG) PubChem (888)
5	O, P, Q, R (A, B, C, D)	water	water		18.0	169	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	79932.1
Non-Polymers*	Number of molecules	10
	Total formula weight	1241.5
All*	Total formula weight	81173.6

*Water molecules are not included.