7I9DEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tyrosine-protein kinase BTK | polymer | 169 | 19966.9 | 4 | UniProt (Q06187) Pfam (PF00169) Pfam (PF00779) | Homo sapiens (human) | Agammaglobulinemia tyrosine kinase,ATK,B-cell progenitor kinase,BPK,Bruton tyrosine kinase |
| 2 | E, G, K (A, B, C) | [(3S,3aS,6S,7aR)-6-(2-hydroxyphenyl)octahydro-1-benzofuran-3-yl]methanediol | non-polymer | 264.3 | 3 | Chemie (A1B6M) | |||
| 3 | F, H, L, N (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) PubChem (32051) | |||
| 4 | I, M, O (B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) PubChem (888) | |||
| 5 | J (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 170 (UniProt: Q06187)
| PDB | External Database | Details |
|---|---|---|
| Ser 145 | Cys 145 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 79867.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1163.0 | |
| All* | Total formula weight | 81030.8 |
