7H43
Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with Z1246465616 (A71EV2A-x0541)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protease 2A | polymer | 150 | 16493.3 | 1 | UniProt (Q65900) Pfam (PF00947) | Coxsackievirus A16 | P2A,Picornain 2A,Protein 2A |
| 2 | B (A) | (2R)-3-(3,5-dimethyl-1,2-oxazol-4-yl)-N,N,2-trimethylpropanamide | non-polymer | 210.3 | 1 | Chemie (LJ6) | Coxsackievirus A16 | ||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E, F, G, H (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 5 | Chemie (DMS) | |||
| 5 | I (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | J (A) | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
A: 7 - 150 (UniProt: Q65900)
| PDB | External Database | Details |
|---|---|---|
| Gln 1 | - | expression tag |
| Glu 2 | - | expression tag |
| Gln 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Gly 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16493.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 762.4 | |
| All* | Total formula weight | 17255.7 |
