7H3W
Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with Z1201620232 (A71EV2A-x0514)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Protease 2A | polymer | 150 | 16493.3 | 2 | UniProt (Q65900) Pfam (PF00947) In PDB | Coxsackievirus A16 | P2A,Picornain 2A,Protein 2A |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | Coxsackievirus A16 | ||
| 3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | B | 5-methoxy-1,3-benzothiazol-2-amine | non-polymer | 180.2 | 2 | Chemie (NZ1) | Coxsackievirus A16 | ||
| 5 | water | water | 18.0 | 396 | Chemie (HOH) |
Sequence modifications
A, B: 7 - 150 (UniProt: Q65900)
| PDB | External Database | Details |
|---|---|---|
| Gln 1 | - | expression tag |
| Glu 2 | - | expression tag |
| Gln 3 | - | expression tag |
| Thr 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Gly 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32986.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 569.4 | |
| All* | Total formula weight | 33556.0 |
