7H1V
PanDDA analysis group deposition -- Crystal Structure of ZIKV NS2B-NS3 protease in complex with Z31113727
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Serine protease subunit NS2B | polymer | 46 | 5067.5 | 1 | UniProt (Q32ZE1) Pfam (PF01002) In PDB | Zika virus | Flavivirin protease NS2B regulatory subunit,Non-structural protein 2B |
2 | B | Serine protease NS3 | polymer | 168 | 18117.6 | 1 | UniProt (Q32ZE1) Pfam (PF00949) In PDB | Zika virus | Flavivirin protease NS3 catalytic subunit,Non-structural protein 3 |
3 | B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
4 | B | 1-(pyridin-2-yl)piperidin-4-one | non-polymer | 176.2 | 1 | Chemie (A1AJS) | |||
5 | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 46 - 89 (UniProt: Q32ZE1)
B: 11 - 177 (UniProt: Q32ZE1)
PDB | External Database | Details |
---|---|---|
Ser 44 | - | expression tag |
Met 45 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 10 | - | initiating methionine |
Lys 107 | Arg 1605 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 23185.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 254.3 | |
All* | Total formula weight | 23439.5 |