7GYI

Crystal Structure of HSP72 in complex with ligand 10 at 17.10 MGy X-ray dose.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Heat shock 70 kDa protein 1A	polymer	394	43195.9	1	UniProt (P0DMV8) Pfam (PF00012)	Homo sapiens (human)	Heat shock 70 kDa protein 1,HSP70-1,HSP70.1
2	B, F (A)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4) PubChem (1061)	synthetic construct
3	C (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)	synthetic construct
4	D (A)	8-bromoadenosine	non-polymer		346.1	1	Chemie (GBA) PubChem (18530176) PubChem (177125406) PubChem (96544) PubChem (130421) PubChem (254688) PubChem (34365201) PubChem (44283163) PubChem (46783463) PubChem (688019) PubChem (57191410) PubChem (59848347) PubChem (2777912) PubChem (7070207) PubChem (7070208) PubChem (7166681) PubChem (10521478) PubChem (12939901) PubChem (12939902) PubChem (6932341) PubChem (7070206) PubChem (143156689) PubChem (143538939)	synthetic construct
5	E (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
6	G (A)	water	water		18.0	484	Chemie (HOH)

Sequence modifications

A: 1 - 380 (UniProt: P0DMV8)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ile 381	-	expression tag
Lys 382	-	expression tag
Ser 383	-	expression tag
Thr 384	-	expression tag
Arg 385	-	expression tag
Ala 386	-	expression tag
Ala 387	-	expression tag
Ala 388	-	expression tag
Ser 389	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43195.9
Non-Polymers*	Number of molecules	5
	Total formula weight	622.5
All*	Total formula weight	43818.4

*Water molecules are not included.