7GT3
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOOA000527a
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 321 | 37345.6 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | Homo sapiens (human) | Protein-tyrosine phosphatase 1B,PTP-1B |
| 2 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 3 | A | ethyl (3R,3aS,8bS)-1-acetyl-5-methyl-2,3,3a,8b-tetrahydro-1H-[1]benzofuro[3,2-b]pyrrole-3-carboxylate | non-polymer | 289.3 | 1 | Chemie (A1ABI) | |||
| 4 | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Ser 32 | Cys 32 | engineered mutation |
| Val 92 | Cys 92 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37345.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 411.5 | |
| All* | Total formula weight | 37757.0 |
