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7GQT

Crystal Structure of Werner helicase fragment 517-945 in complex with ATP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRNpolymer43950064.71UniProt (Q14191)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF16124)
Homo sapiens (human)
2B, D
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
3C
(A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
4E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5F
(A)
waterwater18.068Chemie (HOH)
Sequence modifications
A: 517 - 945 (UniProt: Q14191)
PDBExternal DatabaseDetails
Met 516-initiating methionine
Gly 946-expression tag
Gly 947-expression tag
Arg 948-expression tag
Leu 949-expression tag
Glu 950-expression tag
Val 951-expression tag
Leu 952-expression tag
Phe 953-expression tag
Gln 954-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight50064.7
Non-Polymers*Number of molecules4
Total formula weight662.3
All*Total formula weight50727.0
*Water molecules are not included.

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PDB entries from 2024-11-13

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