7G8R
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1270087714
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transforming protein RhoA | polymer | 185 | 20926.0 | 1 | UniProt (P61586) Pfam (PF00071) In PDB | Homo sapiens (human) | Rho cDNA clone 12,h12 |
2 | B | Rho guanine nucleotide exchange factor 2 | polymer | 245 | 28644.2 | 1 | UniProt (Q92974) Pfam (PF00621) In PDB | Homo sapiens (human) | Guanine nucleotide exchange factor H1,GEF-H1,Microtubule-regulated Rho-GEF,Proliferating cell nucleolar antigen p40 |
3 | A | (2R,6S)-2,6-dimethyl-4-(3-methyl-1,2,4-thiadiazol-5-yl)morpholine | non-polymer | 213.3 | 1 | Chemie (Z5Z) | |||
4 | A, B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 5 | Chemie (DMS) | |||
5 | A, B | FORMIC ACID | non-polymer | 46.0 | 13 | Chemie (FMT) | |||
6 | water | water | 18.0 | 428 | Chemie (HOH) |
Sequence modifications
A: 1 - 184 (UniProt: P61586)
B: 206 - 448 (UniProt: Q92974)
PDB | External Database | Details |
---|---|---|
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser 204 | - | expression tag |
Met 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 49570.1 | |
Non-Polymers* | Number of molecules | 19 |
Total formula weight | 1202.3 | |
All* | Total formula weight | 50772.4 |