7G89
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1192341021
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transforming protein RhoA | polymer | 185 | 20926.0 | 1 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (human) | Rho cDNA clone 12,h12 |
| 2 | B (B) | Rho guanine nucleotide exchange factor 2 | polymer | 245 | 28644.2 | 1 | UniProt (Q92974) Pfam (PF00621) | Homo sapiens (human) | Guanine nucleotide exchange factor H1,GEF-H1,Microtubule-regulated Rho-GEF,Proliferating cell nucleolar antigen p40 |
| 3 | C, H (A, B) | 1-(5-amino-2H-isoindol-2-yl)ethan-1-one | non-polymer | 174.2 | 2 | Chemie (ZT7) | |||
| 4 | D, I, J, K (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 5 | E, F, G, L, M... (A, B) | FORMIC ACID | non-polymer | 46.0 | 9 | Chemie (FMT) | |||
| 6 | R, S (A, B) | water | water | 18.0 | 370 | Chemie (HOH) |
Sequence modifications
A: 1 - 184 (UniProt: P61586)
B: 206 - 448 (UniProt: Q92974)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 204 | - | expression tag |
| Met 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49570.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1075.2 | |
| All* | Total formula weight | 50645.3 |
