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7FZY

Crystal Structure of human FABP4 in complex with 6-chloro-4-phenyl-2-piperidin-1-yl-3-(1H-tetrazol-5-yl)quinoline

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AFatty acid-binding protein, adipocytepolymer13515022.21UniProt (P15090)
Pfam (PF00061)
In PDB
Homo sapiens (human)Adipocyte lipid-binding protein,ALBP,Adipocyte-type fatty acid-binding protein,A-FABP,AFABP,Fatty acid-binding protein 4
2A6-chloro-4-phenyl-2-(piperidin-1-yl)-3-(1H-tetrazol-5-yl)quinolinenon-polymer390.91Chemie (65X)
3ASULFATE IONnon-polymer96.11Chemie (SO4)
4ADIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
5A2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.12Chemie (TRS)
6waterwater18.0181Chemie (HOH)
Sequence modifications
A: 0 - 131 (UniProt: P15090)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ser -2-expression tag
His -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight15022.2
Non-Polymers*Number of molecules5
Total formula weight809.4
All*Total formula weight15831.5
*Water molecules are not included.

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PDB entries from 2024-10-09

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