7FZK
Crystal Structure of human FABP4 binding site mutated to that of FABP3 in complex with myristate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Fatty acid-binding protein, adipocyte | polymer | 135 | 15060.2 | 1 | UniProt (P15090) Pfam (PF00061) In PDB | Homo sapiens (human) | Adipocyte lipid-binding protein,ALBP,Adipocyte-type fatty acid-binding protein,A-FABP,AFABP,Fatty acid-binding protein 4 |
2 | A | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
3 | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
A: 0 - 131 (UniProt: P15090)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Leu 23 | Val 24 | engineered mutation |
Thr 40 | Met 41 | engineered mutation |
Leu 51 | Ile 52 | engineered mutation |
Thr 53 | Ser 54 | engineered mutation |
Leu 104 | Ile 105 | engineered mutation |
Leu 115 | Val 116 | engineered mutation |
Leu 117 | Cys 118 | engineered mutation |
Cys 124 | Ser 125 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 15060.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 228.4 | |
All* | Total formula weight | 15288.6 |