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7FTK

Crystal Structure of apo human cyclic GMP-AMP synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Cyclic GMP-AMP synthasepolymer36242404.92UniProt (Q8N884)
Pfam (PF03281)
Pfam (PF20266)
Homo sapiens (human)cGAMP synthase,cGAS,h-cGAS,2'3'-cGAMP synthase,Mab-21 domain-containing protein 1
2C, D
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3E, F
(A, B)
waterwater18.020Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight84809.8
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight84940.6
*Water molecules are not included.

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PDB entries from 2025-07-30

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