Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7FI9

Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BNKG2-D type II integral membrane proteinpolymer13916110.22UniProt (P26718)
Pfam (PF00059)
In PDB
Homo sapiens (Human)Killer cell lectin-like receptor subfamily K member 1,NK cell receptor D,NKG2-D-activating NK receptor
2CMHC class I polypeptide-related sequence Apolymer27531885.61UniProt (Q29983)
Pfam (PF00129)
Pfam (PF07654)
In PDB
Homo sapiens (Human)MIC-A
3B, CGLYCEROLnon-polymer92.12Chemie (GOL)
4waterwater18.0148Chemie (HOH)
Sequence modifications
A, B: 80 - 216 (UniProt: P26718)
PDBExternal DatabaseDetails
Met 78-initiating methionine
Glu 79-expression tag
C: 1 - 274 (UniProt: Q29983)
PDBExternal DatabaseDetails
Met 0-initiating methionine
Asp 8Asn 31engineered mutation
Phe 9Leu 32engineered mutation
Ile 34Leu 57engineered mutation
His 108Gln 131engineered mutation
Trp 120Gln 143engineered mutation
Phe 127Trp 150engineered mutation
Trp 146Leu 169engineered mutation
Phe 157Tyr 180engineered mutation
Arg 161His 184engineered mutation
Ile 177Val 200engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight64106.1
Non-Polymers*Number of molecules2
Total formula weight184.2
All*Total formula weight64290.2
*Water molecules are not included.

222926

PDB entries from 2024-07-24

PDB statisticsPDBj update infoContact PDBjnumon