7FGY
Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with P40, NADPH and dUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 610 | 68842.7 | 4 | UniProt (Q07422) Pfam (PF00186) Pfam (PF00303) | Toxoplasma gondii | DHFR-TS |
| 2 | E, H, K, N (A, B, C, D) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 4 | Chemie (NDP) | |||
| 3 | F, I, L, O (A, B, C, D) | 5-(3-chlorophenyl)-6-[2-(3-phenoxypropoxy)ethyl]pyrimidine-2,4-diamine | non-polymer | 398.9 | 4 | Chemie (4TS) | |||
| 4 | G, J, M, P (A, B, C, D) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 4 | Chemie (UMP) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 363 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 275370.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5810.0 | |
| All* | Total formula weight | 281180.6 |
