7FGI
Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7Gppp-AU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | mRNA-capping enzyme nsP1 | polymer | 552 | 61989.5 | 12 | UniProt (Q8JUX6) Pfam (PF01660) | Chikungunya virus strain S27-African prototype | Non-structural protein 1 |
| 2 | M, N, O, P, Q... (M, N, O, P, Q...) | m7Gppp-AU | polymer | 3 | 1375.8 | 12 | synthetic construct | ||
| 3 | AA, CA, EA, GA, IA... (B, C, D, E, F...) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 4 | BA, DA, FA, HA, JA... (B, C, D, E, F...) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 12 | Chemie (SAH) | |||
| 5 | AB, BB, CB, DB, EB... (Q, R, S, T, U...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 516 (UniProt: Q8JUX6)
| PDB | External Database | Details |
|---|---|---|
| Ala 37 | His 37 | engineered mutation |
| Gly 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Gly 519 | - | expression tag |
| Gly 520 | - | expression tag |
| Ser 521 | - | expression tag |
| Trp 522 | - | expression tag |
| Ser 523 | - | expression tag |
| His 524 | - | expression tag |
| Pro 525 | - | expression tag |
| Gln 526 | - | expression tag |
| Phe 527 | - | expression tag |
| Glu 528 | - | expression tag |
| Lys 529 | - | expression tag |
| Met 530 | - | expression tag |
| Asp 531 | - | expression tag |
| Tyr 532 | - | expression tag |
| Lys 533 | - | expression tag |
| Asp 534 | - | expression tag |
| His 535 | - | expression tag |
| Asp 536 | - | expression tag |
| Gly 537 | - | expression tag |
| Asp 538 | - | expression tag |
| Tyr 539 | - | expression tag |
| Lys 540 | - | expression tag |
| Asp 541 | - | expression tag |
| His 542 | - | expression tag |
| Asp 543 | - | expression tag |
| Ile 544 | - | expression tag |
| Asp 545 | - | expression tag |
| Tyr 546 | - | expression tag |
| Lys 547 | - | expression tag |
| Asp 548 | - | expression tag |
| Asp 549 | - | expression tag |
| Asp 550 | - | expression tag |
| Asp 551 | - | expression tag |
| Lys 552 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 760383.8 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 5689.5 | |
| All* | Total formula weight | 766073.3 |
