7FGI
Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7Gppp-AU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | mRNA-capping enzyme nsP1 | polymer | 552 | 61989.5 | 12 | UniProt (Q8JUX6) Pfam (PF01660) In PDB | Chikungunya virus (strain S27-African prototype) (CHIKV) | Non-structural protein 1 |
| 2 | L, H, D, I, E... | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 3 | L, H, D, I, E... | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 12 | Chemie (SAH) | |||
| 4 | C, L, H, D, I... | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 787.4 | 12 | Chemie (GTA) | |||
| 5 | C, L, H, D, I... | URIDINE-5'-MONOPHOSPHATE | non-polymer | 324.2 | 12 | Chemie (U) | |||
| 6 | G, C, L, H, D... | GUANOSINE-5'-MONOPHOSPHATE | non-polymer | 363.2 | 12 | Chemie (G) | |||
| 7 | G, C, L, H, D... | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 516 (UniProt: Q8JUX6)
| PDB | External Database | Details |
|---|---|---|
| Ala 37 | His 37 | conflict |
| Gly 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Gly 519 | - | expression tag |
| Gly 520 | - | expression tag |
| Ser 521 | - | expression tag |
| Trp 522 | - | expression tag |
| Ser 523 | - | expression tag |
| His 524 | - | expression tag |
| Pro 525 | - | expression tag |
| Gln 526 | - | expression tag |
| Phe 527 | - | expression tag |
| Glu 528 | - | expression tag |
| Lys 529 | - | expression tag |
| Met 530 | - | expression tag |
| Asp 531 | - | expression tag |
| Tyr 532 | - | expression tag |
| Lys 533 | - | expression tag |
| Asp 534 | - | expression tag |
| His 535 | - | expression tag |
| Asp 536 | - | expression tag |
| Gly 537 | - | expression tag |
| Asp 538 | - | expression tag |
| Tyr 539 | - | expression tag |
| Lys 540 | - | expression tag |
| Asp 541 | - | expression tag |
| His 542 | - | expression tag |
| Asp 543 | - | expression tag |
| Ile 544 | - | expression tag |
| Asp 545 | - | expression tag |
| Tyr 546 | - | expression tag |
| Lys 547 | - | expression tag |
| Asp 548 | - | expression tag |
| Asp 549 | - | expression tag |
| Asp 550 | - | expression tag |
| Asp 551 | - | expression tag |
| Lys 552 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 743873.7 | |
| Non-Polymers* | Number of molecules | 72 |
| Total formula weight | 23387.6 | |
| All* | Total formula weight | 767261.3 |
