7FGI
Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7Gppp-AU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | mRNA-capping enzyme nsP1 | polymer | 552 | 61989.5 | 12 | UniProt (Q8JUX6) Pfam (PF01660) | Chikungunya virus strain S27-African prototype | Non-structural protein 1 |
| 2 | M, N, O, P, Q... (M, N, O, P, Q...) | m7Gppp-AU | polymer | 3 | 1375.8 | 12 | synthetic construct | ||
| 3 | AA, CA, EA, GA, IA... (B, C, D, E, F...) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 4 | BA, DA, FA, HA, JA... (B, C, D, E, F...) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 12 | Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 5 | AB, BB, CB, DB, EB... (Q, R, S, T, U...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) PubChem (888) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 516 (UniProt: Q8JUX6)
| PDB | External Database | Details |
|---|---|---|
| Ala 37 | His 37 | engineered mutation |
| Gly 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Gly 519 | - | expression tag |
| Gly 520 | - | expression tag |
| Ser 521 | - | expression tag |
| Trp 522 | - | expression tag |
| Ser 523 | - | expression tag |
| His 524 | - | expression tag |
| Pro 525 | - | expression tag |
| Gln 526 | - | expression tag |
| Phe 527 | - | expression tag |
| Glu 528 | - | expression tag |
| Lys 529 | - | expression tag |
| Met 530 | - | expression tag |
| Asp 531 | - | expression tag |
| Tyr 532 | - | expression tag |
| Lys 533 | - | expression tag |
| Asp 534 | - | expression tag |
| His 535 | - | expression tag |
| Asp 536 | - | expression tag |
| Gly 537 | - | expression tag |
| Asp 538 | - | expression tag |
| Tyr 539 | - | expression tag |
| Lys 540 | - | expression tag |
| Asp 541 | - | expression tag |
| His 542 | - | expression tag |
| Asp 543 | - | expression tag |
| Ile 544 | - | expression tag |
| Asp 545 | - | expression tag |
| Tyr 546 | - | expression tag |
| Lys 547 | - | expression tag |
| Asp 548 | - | expression tag |
| Asp 549 | - | expression tag |
| Asp 550 | - | expression tag |
| Asp 551 | - | expression tag |
| Lys 552 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 760383.8 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 5689.5 | |
| All* | Total formula weight | 766073.3 |
