7FGG
Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | mRNA-capping enzyme nsP1 | polymer | 552 | 62056.5 | 12 | UniProt (Q8JUX6) Pfam (PF01660) | Chikungunya virus strain S27-African prototype (CHIKV) | Nonstructural Protein 1 |
| 2 | AB, CA, EB, GA, KA... (K, E, L, F, G...) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 3 | BB, DA, FB, HA, LA... (K, E, L, F, G...) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 12 | Chemie (SAH) | |||
| 4 | AA, CB, EA, GB, IA... (D, K, E, L, F...) | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 538.2 | 12 | Chemie (MGP) | |||
| 5 | BA, DB, FA, HB, JA... (D, K, E, L, F...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 6 | IB, JB, KB, LB, MB... (A, B, C, D, E...) | water | water | 18.0 | 1764 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 516 (UniProt: Q8JUX6)
| PDB | External Database | Details |
|---|---|---|
| Gly 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Gly 519 | - | expression tag |
| Gly 520 | - | expression tag |
| Ser 521 | - | expression tag |
| Trp 522 | - | expression tag |
| Ser 523 | - | expression tag |
| His 524 | - | expression tag |
| Pro 525 | - | expression tag |
| Gln 526 | - | expression tag |
| Phe 527 | - | expression tag |
| Glu 528 | - | expression tag |
| Lys 529 | - | expression tag |
| Met 530 | - | expression tag |
| Asp 531 | - | expression tag |
| Tyr 532 | - | expression tag |
| Lys 533 | - | expression tag |
| Asp 534 | - | expression tag |
| His 535 | - | expression tag |
| Asp 536 | - | expression tag |
| Gly 537 | - | expression tag |
| Asp 538 | - | expression tag |
| Tyr 539 | - | expression tag |
| Lys 540 | - | expression tag |
| Asp 541 | - | expression tag |
| His 542 | - | expression tag |
| Asp 543 | - | expression tag |
| Ile 544 | - | expression tag |
| Asp 545 | - | expression tag |
| Tyr 546 | - | expression tag |
| Lys 547 | - | expression tag |
| Asp 548 | - | expression tag |
| Asp 549 | - | expression tag |
| Asp 550 | - | expression tag |
| Asp 551 | - | expression tag |
| Lys 552 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 744678.5 | |
| Non-Polymers* | Number of molecules | 48 |
| Total formula weight | 12148.1 | |
| All* | Total formula weight | 756826.5 |
