7FFN
Cryo-EM structure of VEEV VLP-LDLRAD3-D1 complex at the 5-fold axes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (K) | Capsid protein | polymer | 275 | 30980.8 | 1 | UniProt (P05674) Pfam (PF00944) | Venezuelan equine encephalitis virus (strain TC-83) (VEEV) | Coat protein,C |
| 2 | B (L) | assembly protein E3 | polymer | 59 | 6488.6 | 1 | UniProt (P05674) Pfam (PF01563) | Venezuelan equine encephalitis virus (strain TC-83) (VEEV) | p130 |
| 3 | C (M) | Low-density lipoprotein receptor class A domain-containing protein 3 | polymer | 80 | 8652.9 | 1 | UniProt (Q86YD5) Pfam (PF00057) | Homo sapiens (Human) | LDLR class A domain-containing protein 3 |
| 4 | D (N) | Spike glycoprotein E2 | polymer | 423 | 47113.7 | 1 | UniProt (P05674) Pfam (PF00943) | Venezuelan equine encephalitis virus (strain TC-83) (VEEV) | p62,pE2 |
| 5 | E (O) | Spike glycoprotein E1 | polymer | 442 | 47952.1 | 1 | UniProt (P05674) Pfam (PF01589) | Venezuelan equine encephalitis virus (strain TC-83) (VEEV) | E1 envelope glycoprotein |
| 6 | F (M) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
K: 1 - 275 (UniProt: P05674)
M: 1 - 70 (UniProt: Q86YD5)
| PDB | External Database | Details |
|---|---|---|
| Asn 64 | Lys 64 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 71 | - | expression tag |
| Pro 72 | - | expression tag |
| Leu 73 | - | expression tag |
| Glu 74 | - | expression tag |
| Val 75 | - | expression tag |
| Leu 76 | - | expression tag |
| Phe 77 | - | expression tag |
| Gln 78 | - | expression tag |
| Gly 79 | - | expression tag |
| Pro 80 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 141188.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 141228.2 |
