7FEW

Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	cAMP-activated global transcriptional regulator Vfr	polymer	213	24063.7	1	UniProt (P55222) Pfam (PF00027) Pfam (PF13545)	Pseudomonas aeruginosa PAO1
2	B (B)	cAMP-activated global transcriptional regulator Vfr	polymer	213	24049.7	1	UniProt (P55222) Pfam (PF00027) Pfam (PF13545)	Pseudomonas aeruginosa PAO1
3	C, H (A, B)	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	2	Chemie (CMP) PubChem (176488666) PubChem (6076) PubChem (23902375) PubChem (25322948) PubChem (40467852) PubChem (44629928) PubChem (25322946) PubChem (56973690) PubChem (216878) PubChem (59909322) PubChem (59968988) PubChem (70878457) PubChem (59350541) PubChem (3080770) PubChem (3246347) PubChem (274) PubChem (6604194) PubChem (6603718) PubChem (6713792) PubChem (6714006) PubChem (124132380) PubChem (12071879) PubChem (12866365) PubChem (163043517) PubChem (129317551) PubChem (131841987) PubChem (134693155) PubChem (138107790) PubChem (163043518)
4	D, E, F, G, I... (A, B)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
5	N, O (A, B)	water	water		18.0	340	Chemie (HOH)

Sequence modifications

A: 5 - 214 (UniProt: P55222)

PDB	External Database	Details
Thr 2	-	expression tag
Gly 3	-	expression tag
Gly 4	-	expression tag

B: 5 - 214 (UniProt: P55222)

PDB	External Database	Details
Thr 2	-	expression tag
Gly 3	-	expression tag
Gly 4	-	expression tag
Asn 175	Gln 175	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48113.4
Non-Polymers*	Number of molecules	11
	Total formula weight	1523.0
All*	Total formula weight	49636.4

*Water molecules are not included.