7FEI

Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody R55

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (1)	Capsid protein VP0	polymer	212	23402.7	1	UniProt (E7D639) Pfam (PF22663)	Foot-and-mouth disease virus - type A	A/WH/CHA/09 VP1, Capsid protein VP1,Capsid protein VP3,Genome polyprotein,P1C,P1D,Virion protein 1,Virion protein 3
2	B (2)	Capsid protein VP0	polymer	218	24541.6	1	UniProt (J9PFK1) Pfam (PF00073) UniProt (by SIFTS) (D0E7R9)	Foot-and-mouth disease virus - type A	A/WH/CHA/09 VP2, Capsid protein VP1,Capsid protein VP3,Genome polyprotein,P1C,P1D,Virion protein 1,Virion protein 3
3	C (3)	Capsid protein VP0	polymer	221	24157.0	1	UniProt (U5JG68) Pfam (PF00073) UniProt (by SIFTS) (D0E7S2)	Foot-and-mouth disease virus - type A	A/WH/CHA/09 VP3, Capsid protein VP1,Capsid protein VP3,Genome polyprotein,P1C,P1D,Virion protein 1,Virion protein 3
4	D (4)	Capsid protein VP0	polymer	85	8778.1	1	UniProt (P03309) Pfam (PF08935)	Foot-and-mouth disease virus - type A (FMDV)	A/WH/CHA/09 VP4, VP4-VP2
5	E (H)	IG HEAVY CHAIN VARIABLE REGION	polymer	126	13615.2	1		Bos taurus
6	F (L)	IG LAMDA CHAIN VARIABLE REGION	polymer	123	12886.9	1		Bos taurus

Sequence modifications

1: 1 - 212 (UniProt: E7D639)

PDB	External Database	Details
Asn 133	Thr 133	conflict
Lys 193	Glu 193	conflict

2: 1 - 218 (UniProt: J9PFK1)

PDB	External Database	Details
Lys 2	Asn 288	conflict
Glu 131	Asp 417	conflict
Thr 134	Pro 420	conflict

3: 1 - 221 (UniProt: U5JG68)

PDB	External Database	Details
Arg 40	Gln 344	conflict
Asp 59	Gly 363	conflict
Val 65	Glu 369	conflict
Glu 70	Asp 374	conflict
Thr 131	Glu 435	conflict
Asp 135	Glu 439	conflict

4: 1 - 85 (UniProt: P03309)

PDB	External Database	Details
Ser 57	Thr 258	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	107381.4
All*	Total formula weight	107381.4

*Water molecules are not included.