7FDK

SARS-COV-2 Spike RBDMACSp36 binding to mACE2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Angiotensin-converting enzyme 2	polymer	621	71708.4	1	UniProt (Q8R0I0) Pfam (PF01401) In PDB	Mus musculus (Mouse)	ACE-related carboxypeptidase
2	E	Spike protein S1	polymer	213	24096.1	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
3	A, E	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A: 1 - 615 (UniProt: Q8R0I0)

PDB	External Database	Details
Ala 16	Thr 16	engineered mutation
Gly 220	Asn 220	engineered mutation
His 228	Arg 228	engineered mutation
Lys 309	Gln 309	engineered mutation
Asp 335	Glu 335	engineered mutation
Glu 336	Pro 336	engineered mutation
His 616	-	expression tag
His 617	-	expression tag
His 618	-	expression tag
His 619	-	expression tag
His 620	-	expression tag
His 621	-	expression tag

E: 333 - 526 (UniProt: P0DTC2)

PDB	External Database	Details
Met 320	-	initiating methionine
Phe 321	-	expression tag
Val 322	-	expression tag
Phe 323	-	expression tag
Leu 324	-	expression tag
Val 325	-	expression tag
Leu 326	-	expression tag
Leu 327	-	expression tag
Pro 328	-	expression tag
Leu 329	-	expression tag
Val 330	-	expression tag
Ser 331	-	expression tag
Ser 332	-	expression tag
Asn 417	Lys 417	engineered mutation
His 493	Gln 493	engineered mutation
Tyr 501	Asn 501	engineered mutation
His 527	-	expression tag
His 528	-	expression tag
His 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	95804.5
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	96468.2

*Water molecules are not included.