7FDG

SARS-COV-2 Spike RBDMACSp6 binding to hACE2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Angiotensin-converting enzyme 2	polymer	621	71828.7	1	UniProt (Q9BYF1) Pfam (PF01401) In PDB	Homo sapiens (Human)	Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15
2	E	Spike protein S1	polymer	213	24101.2	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
3	A, E	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)

Sequence modifications

A: 1 - 615 (UniProt: Q9BYF1)

PDB	External Database	Details
His 616	-	expression tag
His 617	-	expression tag
His 618	-	expression tag
His 619	-	expression tag
His 620	-	expression tag
His 621	-	expression tag

E: 333 - 526 (UniProt: P0DTC2)

PDB	External Database	Details
Met 320	-	initiating methionine
Phe 321	-	expression tag
Val 322	-	expression tag
Phe 323	-	expression tag
Leu 324	-	expression tag
Val 325	-	expression tag
Leu 326	-	expression tag
Leu 327	-	expression tag
Pro 328	-	expression tag
Leu 329	-	expression tag
Val 330	-	expression tag
Ser 331	-	expression tag
Ser 332	-	expression tag
Tyr 501	Asn 501	engineered mutation
His 527	-	expression tag
His 528	-	expression tag
His 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	95929.9
Non-Polymers*	Number of molecules	5
	Total formula weight	1106.0
All*	Total formula weight	97035.9

*Water molecules are not included.