7FCQ
Crystallographic structure of neutralizing antibody P14-44 in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Spike protein S1 | polymer | 203 | 22718.5 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 2 | B (H) | P14-44 antibody Fab fragment heavy chain | polymer | 235 | 25477.5 | 1 | Homo sapiens | ||
| 3 | C (L) | P14-44 antibody Fab fragment light chain | polymer | 216 | 22858.2 | 1 | Homo sapiens | ||
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, F, G (A, L) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | H, I, J (A, H, L) | water | water | 18.0 | 657 | Chemie (HOH) |
Sequence modifications
A: 332 - 528 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Val 330 | - | expression tag |
| Asp 331 | - | expression tag |
| Ser 529 | - | expression tag |
| Arg 530 | - | expression tag |
| Gly 531 | - | expression tag |
| Ser 532 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 71054.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 497.5 | |
| All* | Total formula weight | 71551.6 |
