7FB0

SARS-CoV-2 spike protein in closed state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Spike glycoprotein	polymer	1247	138243.2	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	S glycoprotein,E2,Peplomer protein

Sequence modifications

A, B, C: 1 - 1208 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 682	Arg 682	engineered mutation
Ala 683	Arg 683	engineered mutation
Ser 685	Arg 685	engineered mutation
Pro 986	Lys 986	engineered mutation
Pro 987	Val 987	engineered mutation
Leu 1209	-	expression tag
Val 1210	-	expression tag
Pro 1211	-	expression tag
Arg 1212	-	expression tag
Gly 1213	-	expression tag
Ser 1214	-	expression tag
Gly 1215	-	expression tag
Tyr 1216	-	expression tag
Ile 1217	-	expression tag
Pro 1218	-	expression tag
Glu 1219	-	expression tag
Ala 1220	-	expression tag
Pro 1221	-	expression tag
Arg 1222	-	expression tag
Asp 1223	-	expression tag
Gly 1224	-	expression tag
Gln 1225	-	expression tag
Ala 1226	-	expression tag
Tyr 1227	-	expression tag
Val 1228	-	expression tag
Arg 1229	-	expression tag
Lys 1230	-	expression tag
Asp 1231	-	expression tag
Gly 1232	-	expression tag
Glu 1233	-	expression tag
Trp 1234	-	expression tag
Val 1235	-	expression tag
Leu 1236	-	expression tag
Leu 1237	-	expression tag
Ser 1238	-	expression tag
Thr 1239	-	expression tag
Phe 1240	-	expression tag
Leu 1241	-	expression tag
His 1242	-	expression tag
His 1243	-	expression tag
His 1244	-	expression tag
His 1245	-	expression tag
His 1246	-	expression tag
His 1247	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	414729.6
All*	Total formula weight	414729.6

*Water molecules are not included.