7FAL
Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with T36 and L-pro
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Prolyl-tRNA synthetase (ProRS) | polymer | 500 | 57937.3 | 2 | UniProt (A0A7J6JUK2) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) | Toxoplasma gondii | |
| 2 | C, E (A, B) | 4-[(3R)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide | non-polymer | 486.5 | 2 | Chemie (1T0) | |||
| 3 | D, F (A, B) | PROLINE | non-polymer | 115.1 | 2 | Chemie (PRO) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, B: 334 - 830 (UniProt: A0A7J6JUK2)
| PDB | External Database | Details |
|---|---|---|
| Gly 331 | - | expression tag |
| Ala 332 | - | expression tag |
| Met 333 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115874.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1203.3 | |
| All* | Total formula weight | 117077.9 |
