7F9L

Crystal structure of the variable region of Plasmodium RIFIN #6 (PF3D7_1400600) in complex with LAIR1 (with T67L, N69S and A77T mutations)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Rifin	polymer	163	17002.5	6	UniProt (Q8IM82) Pfam (PF02009)	Plasmodium falciparum (isolate 3D7)
2	G, H, I, J, K... (G, H, I, J, K...)	Leukocyte-associated immunoglobulin-like receptor 1	polymer	110	12436.6	6	UniProt (Q6GTX8) Pfam (PF13895)	Homo sapiens (Human)	LAIR-1,hLAIR1
3	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	154	Chemie (HOH)

Sequence modifications

G, H, I, J, K, L: 22 - 122 (UniProt: Q6GTX8)

PDB	External Database	Details
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
His 21	-	expression tag
Leu 67	Thr 67	engineered mutation
Ser 69	Asn 69	engineered mutation
Thr 77	Ala 77	engineered mutation
Ala 123	-	expression tag
Ala 124	-	expression tag
Ala 125	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	176635.0
All*	Total formula weight	176635.0

*Water molecules are not included.