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7F9A

Homo sapiens Prolyl-tRNA Synthetase (HsPRS) in Complex with L-proline and compound L97

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BBifunctional glutamate/proline--tRNA ligasepolymer50557530.82UniProt (P07814)
Pfam (PF00587)
Pfam (PF03129)
Pfam (PF09180)
In PDB
Homo sapiens (Human)Bifunctional aminoacyl-tRNA synthetase,Cell proliferation-inducing gene 32 protein,Glutamatyl-prolyl-tRNA synthetase
2A, B4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamidenon-polymer477.52Chemie (1XK)
3A, BZINC IONnon-polymer65.42Chemie (ZN)
4A, BCALCIUM IONnon-polymer40.110Chemie (CA)
5ACHLORIDE IONnon-polymer35.53Chemie (CL)
6A, BPROLINEnon-polymer115.12Chemie (PRO)
7waterwater18.0236Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight115061.7
Non-Polymers*Number of molecules19
Total formula weight1823.3
All*Total formula weight116885.0
*Water molecules are not included.

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PDB entries from 2024-07-10

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