7F97
Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with L-proline and compound L97
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Proline--tRNA ligase | polymer | 497 | 57801.2 | 4 | UniProt (Q8I5R7) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) In PDB | Plasmodium falciparum 3D7 | Prolyl-tRNA synthetase,ProRS |
| 2 | A, B, C, D | PROLINE | non-polymer | 115.1 | 4 | Chemie (PRO) | |||
| 3 | A, B, C, D | 4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide | non-polymer | 477.5 | 4 | Chemie (1XK) | |||
| 4 | A | 1,4-BUTANEDIOL | non-polymer | 90.1 | 1 | Chemie (BU1) | |||
| 5 | A, B, C, D | CHLORIDE ION | non-polymer | 35.5 | 10 | Chemie (CL) | |||
| 6 | C | HEXANE-1,6-DIOL | non-polymer | 118.2 | 1 | Chemie (HEZ) | |||
| 7 | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 254 - 746 (UniProt: Q8I5R7)
| PDB | External Database | Details |
|---|---|---|
| Gly 250 | - | expression tag |
| Ala 251 | - | expression tag |
| Met 252 | - | expression tag |
| Ala 253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 231204.8 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2933.5 | |
| All* | Total formula weight | 234138.2 |
