7F80
Co-crystal structure of Inhibitor compound MA-211 in complex with human PPARdelta LBD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peroxisome proliferator-activated receptor delta | polymer | 275 | 31430.5 | 2 | UniProt (Q03181) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta |
| 2 | A, B | (3R)-3-methyl-6-[2-[[5-methyl-2-[4-(trifluoromethyl)phenyl]imidazol-1-yl]methyl]phenoxy]hexanoic acid | non-polymer | 460.5 | 2 | Chemie (1KF) |
Sequence modifications
A, B: 171 - 441 (UniProt: Q03181)
| PDB | External Database | Details |
|---|---|---|
| Gly 167 | - | expression tag |
| Ser 168 | - | expression tag |
| His 169 | - | expression tag |
| Met 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62861.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 921.0 | |
| All* | Total formula weight | 63782.0 |
