7F75
Cryo-EM structure of Spx-dependent transcription activation complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, I (A, B, I) | DNA-directed RNA polymerase subunit alpha | polymer | 314 | 34842.4 | 3 | UniProt (P20429) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) | Bacillus subtilis | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
| 2 | C (C) | DNA-directed RNA polymerase subunit beta | polymer | 1193 | 133847.9 | 1 | UniProt (P37870) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) | Bacillus subtilis | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
| 3 | D (D) | DNA-directed RNA polymerase subunit beta' | polymer | 1199 | 134445.0 | 1 | UniProt (P37871) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) | Bacillus subtilis | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
| 4 | E (E) | DNA-directed RNA polymerase subunit omega | polymer | 67 | 7766.9 | 1 | UniProt (O35011) Pfam (PF01192) | Bacillus subtilis | RNAP omega subunit,RNA polymerase omega 2 subunit,Transcriptase subunit omega |
| 5 | F (F) | RNA polymerase sigma factor SigA | polymer | 371 | 43007.4 | 1 | UniProt (P06224) Pfam (PF03979) Pfam (PF00140) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) | Bacillus subtilis | Sigma-43,Sigma-A,RNA polymerase sigma subunit |
| 6 | G (H) | DNA-directed RNA polymerase subunit epsilon | polymer | 69 | 8263.4 | 1 | UniProt (O31718) Pfam (PF07288) | Bacillus subtilis | RNA polymerase auxiliary subunit epsilon subunit,RNAP epsilon subunit,DNA-directed RNA polymerase subunit omega 1,RNA polymerase epsilon subunit,RNA polymerase omega 1 subunit,Transcriptase subunit epsilon,Transcriptase subunit omega 1 |
| 7 | H (G) | transcriptional regulator Spx | polymer | 131 | 15547.9 | 1 | Pfam (PF03960) UniProt (by SIFTS) (O31602) | Bacillus subtilis | |
| 8 | J (J) | trxA promoter DNA-Non template strand | polymer | 68 | 21202.6 | 1 | Bacillus subtilis | ||
| 9 | K (K) | trxA promoter DNA-template strand | polymer | 68 | 20886.4 | 1 | Bacillus subtilis | ||
| 10 | L (L) | DNA-directed RNA polymerase subunit delta | polymer | 173 | 20417.9 | 1 | UniProt (P12464) Pfam (PF05066) | Bacillus subtilis | RNAP delta factor |
| 11 | M (D) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 12 | N, O (D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 509912.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 155.1 | |
| All* | Total formula weight | 510067.7 |
