7F6J
Crystal structure of the PDZD8 coiled-coil domain - Rab7 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ras-related protein Rab-7a | polymer | 200 | 22649.8 | 2 | UniProt (P51149) Pfam (PF00071) | Homo sapiens (Human) | |
| 2 | C (C) | PDZ domain-containing protein 8 | polymer | 133 | 15086.1 | 1 | UniProt (Q8NEN9) | Homo sapiens (Human) | Sarcoma antigen NY-SAR-84/NY-SAR-104 |
| 3 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, G (A, B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | H, I, J (A, B, C) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 195 (UniProt: P51149)
C: 994 - 1123 (UniProt: Q8NEN9)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Leu 67 | Gln 67 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 991 | - | expression tag |
| Ala 992 | - | expression tag |
| Met 993 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 60385.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1095.0 | |
| All* | Total formula weight | 61480.5 |
