7F62
Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody chAb-25 (Focused refinement of S-RBD and chAb-25 region)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Spike glycoprotein | polymer | 1283 | 142236.3 | 1 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 2 | B (H) | RBD-chAb-25, Heavy chain | polymer | 447 | 48952.8 | 1 | Homo sapiens | ||
| 3 | C (L) | RBD-chAb-25, Light chain | polymer | 215 | 23416.0 | 1 | Homo sapiens |
Sequence modifications
A: 1 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 682 | Arg 682 | conflict |
| Ser 683 | Arg 683 | conflict |
| Ser 685 | Arg 685 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
| Glu 1209 | - | expression tag |
| Phe 1210 | - | expression tag |
| Gly 1211 | - | expression tag |
| Ser 1212 | - | expression tag |
| Gly 1213 | - | expression tag |
| Gly 1214 | - | expression tag |
| Tyr 1215 | - | expression tag |
| Ile 1216 | - | expression tag |
| Pro 1217 | - | expression tag |
| Glu 1218 | - | expression tag |
| Ala 1219 | - | expression tag |
| Pro 1220 | - | expression tag |
| Arg 1221 | - | expression tag |
| Asp 1222 | - | expression tag |
| Gly 1223 | - | expression tag |
| Gln 1224 | - | expression tag |
| Ala 1225 | - | expression tag |
| Tyr 1226 | - | expression tag |
| Val 1227 | - | expression tag |
| Arg 1228 | - | expression tag |
| Lys 1229 | - | expression tag |
| Asp 1230 | - | expression tag |
| Gly 1231 | - | expression tag |
| Glu 1232 | - | expression tag |
| Trp 1233 | - | expression tag |
| Val 1234 | - | expression tag |
| Leu 1235 | - | expression tag |
| Leu 1236 | - | expression tag |
| Ser 1237 | - | expression tag |
| Thr 1238 | - | expression tag |
| Phe 1239 | - | expression tag |
| Leu 1240 | - | expression tag |
| Lys 1241 | - | expression tag |
| Gly 1242 | - | expression tag |
| Gln 1243 | - | expression tag |
| Asp 1244 | - | expression tag |
| Asn 1245 | - | expression tag |
| Ser 1246 | - | expression tag |
| Ala 1247 | - | expression tag |
| Asp 1248 | - | expression tag |
| Ile 1249 | - | expression tag |
| Gln 1250 | - | expression tag |
| His 1251 | - | expression tag |
| Ser 1252 | - | expression tag |
| Gly 1253 | - | expression tag |
| Arg 1254 | - | expression tag |
| Pro 1255 | - | expression tag |
| Leu 1256 | - | expression tag |
| Glu 1257 | - | expression tag |
| Ser 1258 | - | expression tag |
| Arg 1259 | - | expression tag |
| Gly 1260 | - | expression tag |
| Pro 1261 | - | expression tag |
| Phe 1262 | - | expression tag |
| Glu 1263 | - | expression tag |
| Gln 1264 | - | expression tag |
| Lys 1265 | - | expression tag |
| Leu 1266 | - | expression tag |
| Ile 1267 | - | expression tag |
| Ser 1268 | - | expression tag |
| Glu 1269 | - | expression tag |
| Glu 1270 | - | expression tag |
| Asp 1271 | - | expression tag |
| Leu 1272 | - | expression tag |
| Asn 1273 | - | expression tag |
| Met 1274 | - | expression tag |
| His 1275 | - | expression tag |
| Thr 1276 | - | expression tag |
| Gly 1277 | - | expression tag |
| His 1278 | - | expression tag |
| His 1279 | - | expression tag |
| His 1280 | - | expression tag |
| His 1281 | - | expression tag |
| His 1282 | - | expression tag |
| His 1283 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 214605.1 | |
| All* | Total formula weight | 214605.1 |
