7F5B
LBD-TMD focused reconstruction of DNQX-bound GluK2-1xNeto2 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor ionotropic, kainate 2 | polymer | 908 | 102476.0 | 4 | UniProt (P42260) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluK2,Glutamate receptor 6,GluR-6,GluR6 |
| 2 | E (E) | Neuropilin and tolloid-like protein 2 | polymer | 525 | 59413.7 | 1 | UniProt (C6K2K4) Pfam (PF00431) Pfam (PF00057) | Rattus norvegicus (Rat) | Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2 |
| 3 | F, G (F, G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 4 | H, I, K, L, M... (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 5 | J (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | O (D) | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 751.0 | 1 | Chemie (PGT) |
Sequence modifications
A, B, C, D: 1 - 908 (UniProt: P42260)
| PDB | External Database | Details |
|---|---|---|
| Leu 107 | Phe 107 | engineered mutation |
| Val 567 | Ile 567 | variant |
| Cys 571 | Tyr 571 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 469317.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1173.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2118.3 | |
| All* | Total formula weight | 472608.9 |
